Amantadine for fatigue in multiple sclerosis
نویسندگان
چکیده
منابع مشابه
Amantadine therapy for fatigue in multiple sclerosis.
We carried out a double blind control study of fatigue in 32 patients with multiple sclerosis, comparing amantadine hydrochloride 100 mg twice a day and placebo. On amantadine 31% had marked improvement; 15.6% moderate improvement; 15.6% mild improvement; and 36.5% unchanged. On placebo, none noted marked improvement; one claimed moderate improvement on either amantadine or placebo. 18.7% repor...
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Background: Identifying the predictors of pain is important for both health professionals and researchers, because pain has repeatedly been found to be a strong predictor of activity limitations and participation restrictions. The objective of this study was to determine the predictors of pain presence and severity in a large, well-designed sample of community dwelling individuals with multip...
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Fatigue is among the most common, yet least understood, symptoms of multiple sclerosis (MS) [1.]. It can profoundly disrupt the occupational and social functioning of patients, and is recognized as a criterion for MS disability by the Social Security Administration. Most approaches to fatigue assessment can be classified as either self-report scales or performance-based measures of motor or cog...
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F ATIGUE IS ONE OF THE MOST COMMON AND disabling symptoms of multiple sclerosis (MS). Not only does fatigue affect up to 87% of patients with MS but as many as 40% of patients with MS regard fatigue to be their most disabling symptom. Although several therapies have shown some promise in the treatment of fatigue in patients with MS, the lack of a truly effective treatment for this symptom may b...
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Background & Aims: The prevalence of multiple sclerosis (MS) has been on the rise, especially among the youth in Iran. MS is more common in the individuals in their 20s and 40s, while women are also twice as likely to develop MS compared to men. Statistics suggest that there are 2.5 million MS patients worldwide, and this figure has been reported to be 15-30 cases per 100,000 in Iran. According...
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ژورنال
عنوان ژورنال: Cochrane Database of Systematic Reviews
سال: 2007
ISSN: 1465-1858
DOI: 10.1002/14651858.cd002818.pub2